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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4EBP1
All Species:
18.48
Human Site:
S94
Identified Species:
40.67
UniProt:
Q13541
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13541
NP_004086.1
118
12580
S94
D
E
P
P
M
E
A
S
Q
S
H
L
R
N
S
Chimpanzee
Pan troglodytes
XP_001136348
133
14823
E107
L
I
E
D
S
R
V
E
V
N
N
L
N
N
I
Rhesus Macaque
Macaca mulatta
XP_001091933
141
14878
S94
D
E
P
P
T
E
A
S
Q
S
H
L
R
N
S
Dog
Lupus familis
XP_549448
118
12523
S94
E
E
P
P
T
E
P
S
Q
N
H
L
R
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q60876
117
12306
S93
D
E
P
P
M
Q
A
S
Q
S
Q
L
P
S
S
Rat
Rattus norvegicus
Q62622
117
12385
S93
D
E
P
P
M
Q
A
S
Q
S
H
L
H
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514570
67
7606
T44
T
D
E
P
S
T
E
T
T
H
L
H
S
S
H
Chicken
Gallus gallus
XP_424384
116
12481
E93
I
V
E
E
L
K
I
E
N
N
H
V
Q
N
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q98TT6
112
12513
Q89
L
H
P
V
S
K
L
Q
E
L
K
E
E
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120078
115
12648
S92
A
S
P
N
P
L
T
S
V
K
N
Q
I
I
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001077103
113
12005
A89
C
P
E
V
G
A
G
A
E
K
P
N
G
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.6
75.8
94.9
N.A.
90.6
92.3
N.A.
44.9
66
N.A.
56.7
N.A.
N.A.
47.4
N.A.
52.5
Protein Similarity:
100
59.4
80.1
97.4
N.A.
94
95.7
N.A.
49.1
76.2
N.A.
67.8
N.A.
N.A.
65.2
N.A.
66.1
P-Site Identity:
100
13.3
93.3
73.3
N.A.
73.3
80
N.A.
6.6
13.3
N.A.
6.6
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
26.6
93.3
86.6
N.A.
86.6
93.3
N.A.
26.6
46.6
N.A.
20
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
37
10
0
0
0
0
0
10
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
37
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
46
37
10
0
28
10
19
19
0
0
10
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
10
0
0
0
0
0
10
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
10
46
10
10
0
10
% H
% Ile:
10
10
0
0
0
0
10
0
0
0
0
0
10
10
10
% I
% Lys:
0
0
0
0
0
19
0
0
0
19
10
0
0
0
10
% K
% Leu:
19
0
0
0
10
10
10
0
0
10
10
55
0
10
0
% L
% Met:
0
0
0
0
28
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
10
28
19
10
10
46
0
% N
% Pro:
0
10
64
55
10
0
10
0
0
0
10
0
10
0
0
% P
% Gln:
0
0
0
0
0
19
0
10
46
0
10
10
10
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
28
0
10
% R
% Ser:
0
10
0
0
28
0
0
55
0
37
0
0
10
28
46
% S
% Thr:
10
0
0
0
19
10
10
10
10
0
0
0
0
0
0
% T
% Val:
0
10
0
19
0
0
10
0
19
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _